17% of Food-Allergic Children Have Sesame Allergy, NIH Study Shows

Jill Murphy, Assistant Editor
Published Online: Monday, November 4th, 2019
Sesame allergy is common among children with other food allergies, occurring in an estimated 17% of the population, according to researchers at the NIH. In addition, the study found that sesame antibody testing accurately predicts whether a child with food allergy is allergic to sesame.
Led by Pamela A. Frischmeyer-Guerrerio, M.D., Ph.D., the scientists took a different approach to conducting the sesame antibody test. The standard tests are a skin-prick test and the allergen-specific antibody test, which are known for being inconsistent in predicting an allergic reaction to sesame. In this test, 119 children with food allergies whose sesame-allergic status was unknown were evaluated.
The participants were offered an oral food challenge, which involved ingesting gradually increasing amounts of sesame under medical supervision to see if an allergic reaction occurred. Children who experienced a recent allergic reaction to sesame or were known to tolerate concentrated sesame in their diet were not offered an oral food challenge.
The study found that 15 of the 119 children were sesame-allergic, 73 were sesame-tolerant, and sesame-allergic status could not be determined for 31 children due to their decline to the oral food challenge. 17% of the 88 children whose sesame-allergic status was definitive had a sesame allergy.
Sesame-specific immunoglobulin E (slgE) was measured in the 88 children, which was used to develop a mathematical model for predicting the probability that a child with food allergies is allergic to sesame. With this model, children with more than 29.4 kilo (international units) of slgE per liter of serum have a greater than 50% chance of being allergic to sesame. However, this model will need to be validated by additional studies before it can be used in clinical practice.

Sesame Now the Ninth Most Common Food Allergy in US
NIH researchers estimate 17% of food-allergic children have sesame allergy [news release]. Bethesda, MD; NIH News Releases: November 4, 2019. https://www.nih.gov/news-events/news-releases/nih-researchers-estimate-17-food-allergic-children-have-sesame-allergy. Accessed November 4, 2019.

Current Issue

The Educated Patient

Katarzyna Lalicata, MSN, FNP-C, FNP-BC
The symptoms associated with colds, most commonly congestion, coughing, sneezing, and sore throats, are the body's response when a virus exerts its effects on the immune system. Cold symptoms peak at about 1 to 2 days and last 7 to 10 days but can last up to 3 weeks.
Kristen L. Marjama, DNP, APRN-BC, FNP
Exposure to damp and moly environments may also result in a variety of other health issues.
Bethany Rettberg, NPC
An accurate medical history and a physical exam are critical to rule out more serious conditions.
Bethany Rettberg, NPC
Practitioners should get a detailed medical history and conduct a thorough physical to treat sinus infections.
$vacMongoViewPlus$ $vAR$
Contemporary Clinic
MJH Associates
American Journal of Managed Care
MD Magazine
Pharmacy Times
Specialty Pharmacy Times
Targeted Oncology
About Us
Contact Us
Terms & Conditions
Pharmacy Healthcare & Communications, LLC
2 Clarke Drive
Suite 100
Cranbury, NJ 08512
P: 609-716-7777
F: 609-257-0701

Copyright Contemporary Clinic 2019
Pharmacy Healthcare & Communications, LLC. All Rights Reserved.